by Jen » Sun Jul 10, 2011 10:51 pm
Hi WW. I think I know the exact study you are referring to. Is it “Fasciotomy Worsens the Amount of Myonecrosis in a Porcine Model of Crotaline Envenomation” by DA Tanen, DC Danish et al; Ann Emerg Med. 2004;44:99-104?
There are a few important points about this study:
1) It is an animal study. Pigs are as close as possible to people, but they are still pigs
2) The authors performed the fasciotomy immediately following injection of the venom. They did not wait for the development of raised intra-compartmental pressures
3) There was more myonecrosis following fasciotomy. This does not actually surprise me as during fasciotomy, scalpels & diathermy (electric current) are applied to the tissues so there will definitely be tissue damage. A fasciotomy is not innocuous. The important issue is whether this microscopic increased myonecrosis is actually clinically relevant.
This study would have been of way more benefit if the authors had actually waited for raised compartmental pressures, done a fasciotomy on half the subjects and not done on the other half & THEN examined the muscle microscopically. In my opinion, the results would have been more relevant. This study is also quite old (2004) and unfortunately there has been no follow up study.
Don’t get me wrong – I am not a fan of fasciotomies. I do believe that they are truly the last resort and should be reserved for a limb saving procedure. I do also feel that because of idiotic cowboy doctors & multiple horror stories, snake keepers have become “anti-fasciotomy” to the extreme.
1.1.0 Epicrates cenchria cenchria
1.1.0 Corallus hortulanus
1.1.0 Heterodon nasicus
1.1.0 Trimeresurus puniceus
2.2.0 Trimeresurus albolabris